Just south of Quincy IL., south off I- 72 is Kinderhook IL. Take Hwy #96. When #96 turns east, just south of Mozier, continue south through Hamburg and Batchtown.A left on Schleeper rd. and then a right at the T intersection, will lead you first to Brussels Ferry, then south on the Great River Road to Grafton.
Although not a official/government named extention of the Great River Road US Scenic Byway, if you like the Great River Road, this route is a great way to extend your drive. The roads skirt the Mississippi River Bluffs for most of your trip. A lot of rural scenery and rustic beauty. Flat farm land to hillside vistas of the Big Muddy.
The first third and last third of this route are excellent paved roads with lane markings. The middle third narrows and is mostly unlined. The narrower sections of this trip is twistier and tighter. Small creek crossing bidges can be rough, but most were improved last year.
Bars and Pubs dot the roadsides. Restaurants in Brussels and Grafton serve a wide variety of local fare, wines and spirits.
Motorcycle Road Additional info
On the narrow, unlined sections, let your riding ability and road surfaces dictate your speed. Some turns are quite tight and challenging. When cresting rises, stay single file and to the right.
Nice route from Lousiana, MO to Hannibal, MO on Rt 79 al so from Lousiana to where two rivers meet take 96 down to county 2 and you'll end up down in Brussels where you can take the ferry across the IL to rt 100 and ride back up North to Hardin x the river again up to Kampsville and back on 96. We did in about 3hrs beautiful county 2 winds and dips goes through woods and over a few 20ft long gravel spots but rest is all paved. Get gas before you go! I didn't see one gas stop just bars.