Start
your route in Washington,
MO (which is about 50 miles west of downtown St. Louis).
From Washington, MO its easy to describe as all you do
is go west on Missouri Route 100 all the way to Linn Missouri
(just follow the signs and enjoy the awesome scenery).
Between Washington and Linn you'll pass through New Haven,
Hermann, Gasconade, and Chamois.
Special
note from the submitter: For an excellent fall foliage
ride, I like to go West on 100 to Linn. I then take Hwy
50 to Jefferson City. Cross the river and then go East
on Hwy 94. You'll end up back where you started from.